Eli Lilly CEO on Fighting Obesity, Developing New Drugs
March 12, 2024 / Eli Lilly / Obesity / Drug Development
Watch this Bloomberg video where Eli Lilly’s CEO discusses the company’s strategies and challenges in developing new obesity-fighting drugs. Get an inside look at how these efforts are advancing health and weight management in the pharmaceutical industry. This conversation sheds light on both the progress made and the hurdles yet to overcome. Click for a deeper understanding of these important issues.
89bio kicks off Phase III trial for pegozafermin in MASH
March 12, 2024 / MASH / Phase III Trial / Pegozafermin
89bio has begun a Phase III trial of pegozafermin for non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with advanced fibrosis. The ENLIGHTEN-Fibrosis study, targeting 1,000 patients, will test the efficacy and safety of this recombinant protein for future regulatory approval in the US and Europe. Learn more about how this could change treatment options for MASH patients.
How high blood sugar, hypertension and obesity can add up to cancer risk
March 11, 2024 / Metabolic Syndrome / Cancer Risk / Public Health
A recent study highlights a strong connection between metabolic syndrome, marked by high blood pressure and obesity, and a heightened risk of cancer. This finding emphasizes the critical role of maintaining metabolic health to reduce the risk of cancer. Discover more about how addressing metabolic issues can lead to lower cancer susceptibility.
Obesity associated with poorer mental health, especially in women
March 11, 2024 / Obesity / Mental Health / Gender Differences
New research from University College Cork shows a link between obesity and poorer mental health in middle-aged to older people, notably more pronounced in women, suggesting social and physical factors are contributory.
Worsening metabolic syndrome associated with developing a variety of cancers
March 11, 2024 / Metabolic syndrome / Cancer development / Health risks
Critical findings from a recent study reveal the heightened risk of various cancers in individuals experiencing worsening metabolic syndrome. Understand the crucial importance of regular monitoring and effective management of metabolic health to combat this increased threat. Dive into the research that connects metabolic syndrome with cancer risks and learn how proactive health management can make a difference. Click to gain valuable insights and protective strategies against cancer.
Maternal Obesity and Neonatal Metabolic Health: Insights Into Insulin Resistance
March 10, 2024 / Maternal Obesity / Neonatal Health / Insulin Resistance
Examine the effects of maternal obesity on newborn metabolic health, with a particular focus on insulin resistance. Uncover how the offspring of obese mothers may face increased vulnerability to metabolic alterations. This piece sheds light on the crucial link between maternal health and the long-term metabolic outcomes for children. Learn more about the significant implications and insights this research offers for expecting mothers and healthcare professionals.
Diagnosing diabetes in the blink of an eye
March 10, 2024 / Diabetes Diagnosis, Retinal Images / DiaNet Model
An innovative tool leverages retinal images for the early detection of cardiovascular diseases and classifies common eye conditions, including diabetic retinopathy, diabetic macular edema, and glaucoma. Learn about the significant advancements and the potential impact of DiaNet on healthcare, particularly in early disease detection and management.
Combining GLP-1s with CGM for Improved Type 2 Diabetes Care
March 10, 2024 / Type 2 Diabetes Care / GLP-1 / Continuous Glucose Monitoring (CGM)
There are challenges surrounding access to advanced diabetes technology and the latest medications, such as GLP-1s, due to high costs and shortages. Understand the critical role that ongoing studies play in promoting insurance coverage for these essential treatments in type 2 diabetes care. Discover how these challenges affect patients and what potential solutions could lead to better access and improved health outcomes.
Metabolic syndrome increases mortality risk in women with high-risk HPV
March 9, 2024 / HPV / Cancer
A new study from York University reveals that women with both metabolic syndrome and high-risk HPV strains face a 2.6 times higher mortality risk. The study emphasizes the impact of chronic disease comorbidity on HPV-related cancer risks and underlines the importance of comprehensive healthcare strategies.
Madrigal Shares Soar as FDA Nears Historic MASH Decision
March 9, 2024 / Madrigal / FDA Decision / Resmetirom
Madrigal’s stock experienced a significant surge ahead of the FDA’s impending decision on the MASH drug, resmetirom. Hear from analysts such as Edward Nash and David Lebowitz, who share their positive outlooks, with Nash revising the price target upward and reaffirming a ‘Buy’ rating on Madrigal stock. Uncover what this critical moment could mean for Madrigal Pharmaceuticals and investors alike as anticipation builds around this potential breakthrough in MASH treatment.
CCS Report Reveals Misconceptions Among People Living With Diabetes; Calls for Enhanced Engagement, Education
March 8, 2024 / Diabetes Management / Weight Loss / Patient Education
A survey by CCS indicates many individuals with diabetes have misconceptions about GLP-1 weight loss drugs as a sole solution for health goals, highlighting the need for more comprehensive diabetes management and education.
Biological aging as a predictor of cardiometabolic multimorbidity
March 8, 2024 / Cardiometabolic Multimorbidity / Observational Data
Recent UK Biobank analysis reveals higher biological age is linked to increased cardiometabolic disease risk, although its ability to predict multimorbidity progression is limited.
Steatotic liver disease: a new name to reflect the combined role of alcohol and metabolic dysfunction
March 8, 2024 / Non-Alcoholic Fatty Liver Disease
Gain fresh perspectives from our latest article that introduces ‘steatotic liver disease’ as a pivotal term, calling for enhanced research and innovative treatment methods. Dive into the combined impacts of alcohol consumption and metabolic dysfunction on liver health. This piece argues for a unified approach in understanding and combating liver disease, underlining the necessity for advanced studies and interventions. Learn more about the evolving landscape of liver health and the strides being made towards better treatment solutions.
Role of IL-18 in adipose tissue remodeling and metabolic dysfunction
March 8, 2024 / Obesity / Adipose tissue / IL-18
Uncover the protective role of IL-18 in combatting obesity and metabolic dysfunction. Discover groundbreaking research demonstrating the significant effects of IL-18 deficiency, including increased adiposity, heightened levels of proinflammatory cytokines in mice, and altered glucose metabolism. This piece provides crucial insights into how IL-18 functions as a key player in maintaining metabolic health and offers potential avenues for therapeutic interventions.
Inclusive Health: Creating Access to Type 1 Diabetes Screening in Underserved Communities
March 8, 2024 / T1D Screening / Underserved Communities / JDRF
Early detection and education for Type 1 Diabetes (T1D) is critical for managing this condition. Learn how individuals affected by T1D are making a difference by educating others about diabetes management and recognizing symptoms early. The piece also delves into the efforts of organizations such as JDRF in increasing awareness and spearheading initiatives that support the T1D community. Understand the impact of community support and awareness in battling Type 1 Diabetes.
Gut Microbiome Drives Metabolic Diseases in Post-Menopausal Mice
March 6, 2024 / Menopause / Gut Microbiome / Metabolic Disease
Research reveals that post-menopausal mice experience changes in gut microbiome leading to increased risk of metabolic diseases, highlighting the influence of female sex hormones on microbiome composition and health.
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease
March 6, 2024 / Diabetic Kidney Disease / Metabolic Differences
Research reveals significant metabolic differences between males and females in diabetic kidney disease, potentially explaining the sex-dependent disease outcomes and highlighting the role of metabolic pathways in treatment.
Genome-wide characterization of circulating metabolic biomarkers
March 6, 2024 / Metabolic Biomarkers / Genome-Wide Association,
There is a significant role of genetic variations that influence metabolic traits, thereby affecting conditions such as diabetes. Through comprehensive genome-wide association analysis of circulating metabolites, this research sheds light on how specific genetic differences can lead to varied metabolic profiles. Learn about the deep connections between genetics and metabolism and how this knowledge could revolutionize the approach to diagnosing and managing metabolic diseases.
Novo Nordisk’s Semaglutide’s Multi-Beneficial Effects: Weight Loss, Improved Metabolic Markers, Liver Fat Reduction in HIV-Related Liver Disease
March 6, 2024 / Semaglutide / HIV-Related Liver Disease
Discover the latest findings from a recent study highlighted in our article, which showcases the benefits of semaglutide for HIV patients suffering from liver disease. Understand how this treatment leads to significant weight loss, liver fat reduction, and improvements in metabolic indicators. Delve into the research that could redefine the management of liver disease in HIV-positive individuals and explore the potential changes in treatment protocols based on these promising results.
Lindus jumps on GLP-1 hype with ‘all-in-one’ CRO package for metabolic disease
March 6, 2024 / Metabolic Drugs / GLP-1
Lindus Health has launched a comprehensive CRO service targeting metabolic diseases and diabetes, tapping into the rising demand for GLP-1 based therapies and other metabolic treatments.
New study connects lack of sleep with diabetes
March 6, 2024 / Diabetes Risk / Type 2 Diabetes
Sleeping less than six hours per night significantly increases the risk of developing Type 2 diabetes, regardless of diet quality. Understand the profound impact that insufficient sleep has on escalating diabetes risk and why lifestyle factors play an essential role in the development of chronic diseases. Dive into the details of this research to learn how adjusting sleep patterns could be a key strategy in preventing Type 2 diabetes.
After obesity drugs’ success, companies rush to preserve skeletal muscle
March 5, 2024 / Obesity Drugs / Skeletal Muscle Preservation
There is a new focus for companies on preserving skeletal muscle following the success of obesity drugs. Discover why maintaining muscle mass and function is becoming a crucial element in obesity treatment strategies. This piece highlights the shift in attention towards ensuring that weight loss does not come at the expense of muscle health. Learn about the latest advancements and the significance of balancing muscle preservation with effective obesity management.
Konjac Glucomannan: A functional food additive for preventing metabolic syndrome
March 5, 2024 / Metabolic Syndrome Prevention / Gut Health
Konjac Glucomannan (KGM) is explored as a dietary fiber that combats metabolic syndrome by improving gut health, reducing diabetes and obesity risks, and lowering blood pressure and lipid levels.
A probiotic for metabolic liver diseases?
March 5, 2024 / Metabolic dysfunction / Probiotics
Investigate the potential of Adlercreutzia equolifaciens, a common gut bacterium, as a promising probiotic treatment for metabolic liver diseases. Learn how this bacterium can play a crucial role in reducing inflammation and disease severity, offering new hope for those suffering from these conditions. This research opens up new avenues for understanding the gut-liver axis and the development of innovative therapeutic strategies.
Higher blood caffeine levels linked to lower obesity and osteoarthritis risk
March 5, 2024 / Caffeine and Health / Obesity Prevention
A new study by Imperial College London and the University of Copenhagen suggests that higher caffeine levels in blood may lower risks of obesity and osteoarthritis, providing insights into caffeine’s broad health impacts.
Waist-to-height ratio detects fat obesity in children and adolescents significantly better than BMI
March 5, 2024 / Child Health / Obesity Measurement
New research highlights the waist-to-height ratio as a superior indicator for identifying obesity in children and adolescents, surpassing the accuracy of the traditional BMI method.
Cardio-Kidney-Metabolic Syndrome
Cardiovascular
Chronic Kidney Disease
Diabetes
Drug Development
Liver Disease
MASH
Metabolic Health
Obesity
Women’s Health